Intra-Prostatic Injection of Epinephrine during Transurethral Resection of Prostate Reduces Blood Loss and Need for Blood Transfusions

Aim: To assess the role of Intraprostatic injection epinephrine intra-operatively in patients undergoing TURP decreasing blood loss and need for subsequent transfusions. Design: A double-blind, randomized controlled trial. Place duration study: The Kidney Centre Postgraduate Training Institute, Karachi, from March till August 2020. Methodology: total 40 were chosen at random divided into two groups equal size. One group got an intra-prostatic epinephrine, whereas other received a standard saline injection. Both evaluated terms prostate volume (ml), resected tissue (gms), surgical resection time (minutes), pre post-operative Hemoglobin (HB), Hematocrit (HCT) levels. Intra-operative was then quantified using last variables. Transfusion requirement both also recorded. Results: Mean +Age Group B 66.30+9.24years 65.65+7.43years, respectively, with no significant difference between (p=0.808). Median IQR Prostatic 68.0, 15, 64.0,21, suggesting statistically (p=0.372). + S.D Loss HB 1.15 0.42 1.87+1.04, (p=0.007). post-op HCT 3.16+1.50 4.81+2.79, revealing (p=0.026). No needed transfusions, six had indicating statistical distinction (p=0.001). Conclusion: use leads to reduced subsequently operative time, irrigation fluid usage, transfusion during TURP. It allows greater amount prostatic be resected. Keywords: Transurethral Prostate, Epinephrine, Blood transfusion, Hemoglobin, Hematocrit.